Bis(mandelato)borate: an effective, inexpensive spiroborate anion for chiral resolution.

نویسندگان

  • Lawrence W-Y Wong
  • Jack W-H Kan
  • Thanh-ha Nguyen
  • Herman H-Y Sung
  • Dang Li
  • Alex S-F Au-Yeung
  • Rajpal Sharma
  • Zhenyang Lin
  • Ian D Williams
چکیده

Bis(mandelato)borate [B(Man)2](-) (R- or S-) anions are simply prepared and appear widely effective for resolution of racemic cations. Three examples demonstrate their scope; the alkaloid tetrahydropalmatine (THP), 1,2-diaminopropane (1,2-dap) and the metal-organic complex [Co(phen)3](3+) are readily resolved, either by a facile one-pot procedure, or via counter-ion metathesis.

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عنوان ژورنال:
  • Chemical communications

دوره 51 87  شماره 

صفحات  -

تاریخ انتشار 2015